Input / output puzzles

There is this program that takes a word as input, processes them,
and gives out a letter or number as output. The exact process
used to process the words, though, varies wildly.

The different sets of words below each use a totally different rule for
processing. Each word in a given set, though, will be processed
by the same rule. In each set, I'll give you some sample words
and their results, and it's your job to figure out the rule
that's used, and (using this rule) what the remaining
two answers (those ending in question marks) are.
.
~~~'***'~~~

Set # 1: WEDDING=1 FAN=0 EXTREME=3 SHAMROCKS=0 PLEASE=2 ENVELOPE=? HAZARD=?	Answer 1
Set # 2: TREASURE=U BAGEL=L CHIMPANZEE=Z ARISEN=S CABBAGE=G ARMADILLO=? YELLOW=?	Answer 1
Set # 3: SCREW=2 RATE=8 HERO=0 SCORE=4 CHICKS=6 SIGN=? HEAVEN=?	Answer 1
Set # 4: GASBAGS=B LEVEL=V RETREAT=A DEIFIED=F HORSESHOE=R ILL=? TOSSPOT=?	Answer 1
Set # 5: ALLERGY=L SPIRE=S TRANQUIL=N SUSPICION=I MARSHMALLOW=A FIREWORKS=? SANDWICH=?	Answer 1
Set # 6: RED=C BLUE=J GREEN=T EVIL=I POOL=Q HONEY=? THANK=?	Answer 1
Set # 7: VEXATION=16 CIVILITY=158 COCCYX=310 PIXEL=61 BIKINI=3 LLAMA=? DIMMED=?	Answer 1
Set # 8: SEE=5 LIGHT=10 EARLY=9 SAY=2 LAST=19 BY=? PROUDLY=?	Answer 1
Set # 9: FATHOMS=G FREE=D INTERMISSION=L SHINE=E COUNTERCLOCKWISE=P CHORUS=? HIS=?	Answer 1
Set #10: DUPLEX=2 SUCCESS=0 ABROAD=6 LEGROOM=3 BOOZER=4 GUMDROP=? TELEPHONE=?	Answer 1
Set # 11: FOGGY=G MONSTER=N UNCOVER=V PIQUE=Q BOOKMARK=C OXYGEN=? HYPNOTIZE=?	Answer 1
Set # 12: ASTEROID=A BREAK=R CONVERT=N DENOTING=O EXPERT=P FINAGLE=? GYRATE=?	Answer 1
Set # 13: MINIMUM=6 TELEVISE=7 YOURSELF=4 SPROUT=1 CELEBRATE=6 SWEATSHIRT=? POTATO=?	Answer 1
Set # 14: STUPID=1 HIPPOPOTAMUS=3 BURLESQUE=2 FLAMINGO=2 MULLIGATAWNY=4 REPORTER=? BEAUTIFUL=?	Answer 1
Set # 15: FASHION=0 DETECTED=8 GIVEN=3 INSPECTED=6 BREEZE=5 PUZZLE=? LULLABY=?	Answer 1
Set #16: GLOSS=14 COOK=11 ABATIC=8 WOP=18 FATTING=? ME=?	Answer 1
Set # 17: DERIVED=8 WEED= 27 FRANTIC=9 GLICH=15 PIGEON=? HI=?	Answer 1
Set # 18: MEXICO=24 IRAK=10 CHINA=1 QATAR=17 GUAM=? POLAND=?	Answer 1
Set # 19: VISCOUNT=3 ARKANSAS=8 PHLEGM=5 GAUGE=3 BALLET=? PSYCHOLOGY=?	Answer 1
Set # 20: AMPERE=D ESCUDO=C ABSOLVE=G TIE=B LACERATE=? AFAR=?	Answer 1
Set # 21: PARKA= P SIXTHS=S UNFUNNY=U QUERN=Q JEST=E NOMAD=? NYALA=?	Answer 1
Set # 22: FRANCIS=6 IRWIN=4 LAWRENCE=5 BENNY=4 ALLISON=? AMY=?	Answer 1
Set # 23: MEGABYTE=6 PARTITION=4 BLOCK=2 SECTOR=1 NIBBLE=? ALLOCATION=?	Answer 1
Set # 24: PROCENT=5 AT=2 EXCLAMATION=1 AND=7 DOLLAR=? GATE=?	Answer 1
Set # 25: DEFEND=N GAFFE=A UTERUS=E DECREE=R MILK= ? POMPONS=?	Answer 1
Set # 26: HAND=16 FINGER=60 NOSE=14 NECK BONE=98 EAR=? CANINE=?	Answer 1

Input & Output Puzzles